How to redeploy configuration

Hi Team,

I want to change the following properties,

values.global.mtls.enabled=true
values.security.selfSigned=false

My question is, how can I change it? Via istioctl or istio_ca or yaml file? Is there some way from install yaml file to redeploy it? Because I installed Istion on my OpenShift via Operatior that use yaml file.

Thanks.

Barry