Istio Load balancing by custom metrics

I understand that Istio load balancing is done with least request, random and round robin.
Is there a way to load balance traffic by cpu/memory and/or http request of the pod?

For based on upstream cpu/memory, no this kind of way, and envoy proxy also does not support it. refer here:
For http request, what do you mean? for the “least request, random, round robin” is already based on http request, and LB to different upstream hosts.

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