Routing between external services using Istio and TLS

I have a Kubernetes cluster that uses MySQL DB as an external service (using RDS service by AWS).
I would like to route the traffic to another MySQL instance using Istio, so that 10% of the traffic will go to the first instance and the other 90% will go to the new MySQL DB instance.
Another issue here is that the new MySQL DB is using TLS.

Is it possible using Istio?

It sounds like you would like to use external services for MySQL and configure request routing with traffic shifting weights.