Use istio ingress gateway as proxy for external services

I am new to istio and we are planning to use Istio as a Proxy for External Services for example enterprise.example.com as root url and other path based traffic to be routed to external services like Azure VM and Azure webapps.

VM App: test.app1.com
Web App: test.app2.com

We want to use proxy url as enterprise.example.com even if the traffic routes to enterprise.example.com/app1 or app2.

Please let me know it is possible to configure with istio.

Thanks and Regards
Gokul