Configure Mesh-Wide Outlier Detection

Networking
1

Is it possible to configure the outlier detection with Global Mesh Options? I am asking, because we want to enable locality based load balancing mesh-wide, but locality only seems to work with configured outlier detection.

My (simplified) operator config looks like this, but it does not seem to have any effect:

apiVersion: install.istio.io/v1alpha1
kind: IstioOperator
metadata:
  namespace: istio-system
  name: defaut
spec:
  profile: default
  meshConfig:
    localityLbSetting:
      enabled: true

Having a specific DestinationRule with an outlier detection works:

apiVersion: networking.istio.io/v1beta1
kind: DestinationRule
metadata:
  name: app
spec:
  host: app.default.svc.cluster.local
  trafficPolicy:
    outlierDetection:
      consecutive5xxErrors: 10
      interval: 1s
      baseEjectionTime: 1m
      maxEjectionPercent: 40
    loadBalancer:
      simple: ROUND_ROBIN
      localityLbSetting:
        enabled: true